Chinese scientists reveal that animals live longer under hypoxic conditions-9c8947

Scientists Chinese secret: hypoxia animal more new network longevity in the September 12 Kunming Xinhua (reporter Ma Qian) 12 reporters from the Kunming Institute of animal research institute was informed that the scientists in the high altitude adaptation genetic mechanism made great progress. The results showed that both the experimental animals and the wild animals showed a longer life under hypoxia. This may also be the cause of Tibetan longevity. The Qinghai Tibet Plateau is the highest plateau in the world, known as the earth’s "third pole", with low oxygen, strong radiation, low temperature. However, with the move of human settlement, a number of domestic animal in such bad environment from generation to generation reproduction, have formed their unique plateau adaptation characteristics, provided rich material for scientists to quickly adapt to the plateau species analysis of genetic mechanism of evolution. Team Zhang Yaping, Kunming Animal Research Institute Wu Dongdong China genomic research based on the data, reveals the Tibetan Plateau using a variety of domestic animal genetic methods, such as genetic mechanism of plateau adaptability of Tibetan mastiff, Tibetan chicken, identified a number of hypoxia induced circuit as the representative of the high altitude adaptation candidate genes, provide important information for the species the Tibetan mastiff resources protection; found in Tibetan chicken is divided into two independent groups, and their evolutionary potential plateau to calcium signaling pathway as the representative of the adaptation mechanism, provide important genetic information for Tibetan chicken germplasm resources protection and cultivation. In recent years, researchers have studied the genetic basis of longevity in Tibetan population under hypoxia. Both the experimental animals and the wild animals showed a longer life under hypoxia. However, in the common understanding in Tibetan population life but life expectancy than plain area population is much shorter, this paradox has been unsolved. "Through the analysis of the National Bureau of statistics released the 2010 census data, found that over 60 years old Tibetan population ratio is significantly lower than the Han population, which may be related to the Qinghai Tibet Plateau harsh living environment, poor medical resources. However, through the evaluation of different types of parameters, we found that the longevity of the elderly over the age of 100 in Tibet area was higher than that in the plain Han nationality, and the relative mortality rate of the elderly in Tibet area was lower than that of the Han people in plain." Zhang Yaping said this and found in another people at high altitude in the Andes natives "longevity village" echoes. The characteristics of longevity may result from genetic differences and senescence related gene in Tibetan population or the Tibetan Plateau in the domestic animal exhibited rapid evolution, and further confirmed the expression of senescence gene has significant differences in the plateau plain domestic animal and domestic animal, and the expression changes with aging in the process of change was negatively correlated, therefore suggesting that hypoxia environment is likely to cause the longevity of the Tibetan population. The results, published online in Cell Research. (end) editor: Sun Ailin SN146相关的主题文章: